China Competitive Price Injection Grade Sodium Hyaluronate Powder Manufacturer, Supplier

Injectable sodium hyaluronate is a high-purity linear mucopolysaccharide prepared by microbial fermentation. It is a naturally occurring physiologically active substance in human tissues and is a core pharmaceutical excipient and implant material in the fields of medicine, aesthetic medicine, orthopedics, and ophthalmology.

Product Description

Product Specification

Model Number FU-2026030
Product Name Sodium Hyaluronate
Chemical Formula (C14H20NNaO11)n
Chemical Structure
Chemical Structure
CAS No. 9067-32-7
Appearance White, fine powder
Assay 95.0%~105.0%
Solubility Soluble in water
Heavy metals ≤ 10ppm
Protein ≤ 0.1%
Bacterial endotoxins ≤ 0.05IU/mg
Source Microbial fermentation

Product Advantages

High Biocompatibility

Naturally present in the human body's dermis, synovial fluid, and vitreous humor, with no immune rejection or racial differences.

High Moisturizing Properties

A single sodium hyaluronate molecule can bind 500-1000 times its own weight in water, maintaining local tissue hydration and elasticity.

Biodegradable

Gradually degraded into monosaccharides by hyaluronidase in the body, with non-toxic and harmless metabolites and no residue accumulation.

High Purity & Low Impurities

Eliminated of allergens such as proteins, nucleic acids, and heavy metals; endotoxin control is stringent, meeting injection safety requirements.

Adjustable Rheological Properties

Viscosity and elasticity can be adjusted through molecular weight and cross-linking processes, adapting to different injection scenarios.

Production Process

1. Strain Selection

Non-pathogenic, high-hyaluronic acid-producing strains are selected, and multiple tests confirm no exogenous contamination.

2. Fermentation Culture

Controlled fermenter culture with precise temperature, pH, and dissolved oxygen control ensures stable polysaccharide polymerization.

3. Separation and Purification

Multi-stage filtration, alcohol precipitation, ion exchange, and ultrafiltration remove impurities such as proteins, nucleic acids, and pigments.

4. Refining and Drying

Vacuum freeze-drying maintains the integrity of the polysaccharide molecular structure, yielding high-purity powder.

5. Dispensing and Sterilization

Aseptic dispensing, irradiation/moist heat sterilization, with a completely closed system to prevent secondary contamination.

6. Comprehensive Testing

Physicochemical, microbiological, and safety indicators are tested batch by batch; only batches that pass the tests are released.

Storage Conditions

Storage

Protect from light, seal tightly, and store in a cool, dry place below 2-10°C. Avoid freezing, high temperatures, and direct sunlight.

Transportation

Transport at room temperature, away from light. Avoid squeezing and collisions; maintain packaging integrity throughout the journey.

Frequently Asked Questions

What is the source of this Sodium Hyaluronate?

The product is derived from microbial fermentation, utilizing non-pathogenic, high-hyaluronic acid-producing strains that are thoroughly tested to confirm zero exogenous contamination.

What makes this product highly biocompatible?

It is naturally present in the human body's dermis, synovial fluid, and vitreous humor. This natural compatibility means it triggers no immune rejection or racial differences.

How much water can a single Sodium Hyaluronate molecule hold?

A single sodium hyaluronate molecule has outstanding moisturizing properties and can bind 500 to 1,000 times its own weight in water, helping to maintain local tissue hydration and elasticity.

What are the storage temperature requirements?

The product should be sealed tightly, protected from light, and stored in a cool, dry place at temperatures between 2-10°C. You should avoid freezing, high temperatures, and direct sunlight.

Is this product safe for injection applications?

Yes. It features high purity with allergens like proteins, nucleic acids, and heavy metals eliminated. The endotoxin levels are strictly controlled (≤ 0.05IU/mg), meeting stringent injection safety standards.

How does it degrade in the body?

It is biodegradable. The substance is gradually broken down into simple monosaccharides by the body's natural hyaluronidase, leaving behind non-toxic, harmless metabolites with no residue accumulation.

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